โNew Approach Promotes Growth of Sound-Detecting Hair Cells,โ Breaking News From M.I.T
BY DR. LOUIS ALPERT
This Ombudsman again thanks Jason Pontin, editor of the โMIT Technology Review,โ for his permission to quote directly from his publication this time on the breakthrough discovery of a possible drug treatment for hearing loss.
The breakthrough was announced earlier this year by MIT scientists together with researchers at the Harvard University Medical School, including doctors at their associated hospitals Brigham and Womanโs Hospital(BWH) and Massachusetts Eye and Ear.
According to MIT, โWithin the inner ear, thousands of hair cells detect sound waves and translate them into nerve signals that allow us to hear speech, music, and other every-day sounds. Damage to these cells is one of the leading causes of hearing loss, which affects 48 million Americans. Each of us is born with about 15,000 hair cells per ear, but noise exposure, aging, and some antibiotics can cause them fatal harm. Humans, unlike some other animals, donโt regenerate these cells when this happens. However, the inner ear does contain progenitor cells that can be induced to multiply and turn into hair cells with a certain combination of drugsโ
Using innovative laboratory techniques, the research team was able to generate an amazing 2,000 times greater number of hair cell progenitors than previous approaches had produced!
โInspired by creatures in nature that exhibit tissue regeneration, the teamโฆdiscovered a small molecule approach to control this process and found it worked for many tissues including the inner ear, to produce large populations of functional sensory hair cells.โ

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